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Specifically, the ACP guideline did not adequately address either the strategy to avoid AHS by starting with a low initial dose of allopurinol before titrating upwards 32 or the valuable role of screening for HLA-B*5801 to identify patients at markedly elevated risk of AHS within multiple well-defined ethnic and racial groups (such as Han Chinese, Korean, Thai, East Indian and African-American populations) 33,34

Glycocalyx A carbohydrate layer on cell surfaces, aiding cellular protection and communication

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5.3 Therapeutic efficacy and safety profiles Efficacy: Multiple in vivo investigations demonstrate that biogenic AgNPs exert dose-dependent tumor growth suppression, apoptosis induction, and metastasis inhibition in oral cancer models (Noga et al., 2023)

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