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Thoughts of suicide had become increasingly commonplace
This antinociceptive profile may reflect DSIPs interaction with endogenous opioid peptide systems and/or NMDA receptor modulation at spinal cord and supraspinal pain processing sites
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Tenforde MW, Yadav A, Dowdy DW, et al

FEBS Lett 579(14):30293036 Zhu H, Jia Z, Misra BR, Zhang L, Cao Z, Yamamoto M, Trush MA, Misra HP, Li Y (2008) Nuclear factor E2-related factor 2-dependent myocardiac cytoprotection against oxidative and electrophilic stress
