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Again, because the precise structure of polysaccharides is not clear, the application of polysaccharides is still only in animal or cell models, and there is not much clinical trial evidence

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However, treatment with Vitamin U alone (100 mg/kg, b.wt, oral) alone, Vitamin-U alone (150 mg/kg, b.wt, oral) alone, Vitamin-U alone (150 mg/kg, b.wt, oral), Vitamin-U (100 mg/kg, b.wt, oral) combined with Vitamin-E (30 mg/kg, b.wt, oral) and Vitamin-E (30 mg/kg, b.wt, oral)significantly cholesterol and TG (except Vitamin-E (30 mg/kg, b.wt, oral)) level decreased compare with the NAFLD control

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Ceruloplasmin, with six copper atoms, oxidizes ferrous iron (Fe 2+ ) to ferric iron (Fe 3+ ), enabling iron transport by transferrin, which maintains iron homeostasis and modulates inflammation in hepatocytes, macrophages, and mammary glands [107,108,109,110]