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Large-scale clinical trials are needed to validate VNS efficacy across diverse PD subtypes and address non-motor symptoms like cognitive impairment and gastrointestinal dysfunction, which have been neglected in prior studies

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Nature 362:5962 Deng H-X, Hentati A, Tainer JA et al (1993) Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase

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These compounds are characterized by their intricate molecular structures, and cocoa contains various subclasses of flavonoids, including catechins, epicatechins, and procyanidins