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This binding depends on the intact N-terminal hexapeptide sequencemechanical shear stress from shaking or direct powder impact can break peptide bonds in that sequence, reducing receptor binding affinity by 1540%

Reprinted in Acta Paedopsychiatrica

Stupnisek et al., 2015) stabilize gastric pentadecapeptide BPC 157, which is effective in wound healing (Figures 16) (Seiwerth et al., 1997
