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L-theanine treatment alleviates allergic symptoms, decreases the levels of IgE, HIS, and mast cell protease-1 (mMCPT-1) in serum, reduces jejunal inflammation and MC degranulation, regulates the differentiation of jejunal CD 4+ T cells to Th1 and Th17 cells, inhibits the differentiation of Th2 and Treg cells and their cytokines, and improves gut-specific immunity

The role of KD in reducing the severity of symptoms in many skin conditions and its beneficial effects on the skin are also gaining recognition (Figure 1, whereas the key mechanisms specifically related to skin health are summarized in Table 2

Journal of Clinical Investigation, 112(3), 567-574

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