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Description
During normoxia, CO produced by the O 2 dependent enzyme haem oxygenase 2 (HO2) binds to the haem of CBS and keeps the enzyme suppressed

As a competitive inhibitor of xCT, it promotes GSH consumption while inhibiting the expression of the antioxidant H2S-producing enzyme cystathionine-synthase (CBS) to achieve oxidative stress toxicity

Electromobility shift assay (EMSA) confirmed a direct interaction between LEC2 and a 21-bp promoter DNA fragment containing this RY motif (Fig

B-12 is safe to take as a supplement to increase your benefits
Absence of testing documentation raises immediate concerns

(Fang et al., 2020)
