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Further, in diazepam tolerance/withdrawal and physical dependence/withdrawal studies [58], BPC 157 coadministration in chronically treated diazepam mice counteracts diazepam tolerance and withdrawal, postpones physical dependence, and prolongs residual diazepam anticonvulsive activity [58]

NSAIDs may increase the risk of a cardiovascular thrombotic event in patients with or without underlying heart disease or risk factors for heart disease