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Although there are several approaches to metabolomics research, the primary focus has historically been on the intracellular metabolome, mainly aimed at exploring cellular metabolism to elucidate its functional mechanisms and responses, which is beneficial not only to disease diagnosis but also to many aspects of toxicology and therapeutics (Doroghazi et al., 2014

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The theory of cell biology in wound healing emphasized that endothelial cells, fibroblasts, and keratinocytes may contribute to the proliferation stage in the wound healing process

A qRT-PCR kit (YEASEN, China, 11184ES) was used for qRT-PCR

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The dengue genome was transcribed as viral RNA in full-length and electroporated into Huh7.5 cells or Huh7-Lunet-T7 RC cells 3 days and 5 days post electroporation, the supernatant was collected, centrifuged, and stored at 80 C