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Richman, P

J Food Qual

doi: 10.1007/s00425-008-0820-3

Development of CIPN is an indication for dose reduction or discontinuation of the relevant chemotherapy agent

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1) and other related metabolites, we further conducted metabolomics analyses by using Abcg2 knockout (KO) mice and Eisai Hyper-bilirubinemia Rats (EHBR is an Abcc2- deficient animal model), because both two ABC transporters play a pivotal role in ATP-dependent biliary excretion of conjugated xenobiotics as components of Phase III machinery