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This ATF4-mediated induction is often triggered by the GCN2-eIF2 pathway when uncharged tRNAs accumulate (a sign of amino acid deprivation) [23]
10.1002/ana.21541 19 BurrJ.SharmaM.SdhofT
"Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia"
10.1007/s00228-005-0068-9 Eur
