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Figures Abstract Congenital hypothyroidism (CH), characterized by insufficient thyroid hormone production at birth, is frequently associated with fatigue, particularly in cases with delayed diagnosis
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In contrast, the lifespan of mitochondrial electron transport chain deficient isp-1 mutant and raga-1 mutants, in which mTOR complex 1 activity is inhibited, remains unaffected by changes in the media (Figure 4C and D), indicating that the lifespan extension effects induced by mitochondria deficiency and TOR inhibition are resilient to environmental factors that interfere with metformin action in aging
The lipid contents also impart unique properties such as viscosity and surface tension to this layer
