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In studies that have investigated the involvement of the IL in regulating conditioned (learned) cardiovascular responses it has been shown that excitotoxic lesions primarily targeting the IL (with variable involvement of the more dorsal prelimbic [PL] subregion) decreased HR responses to a tone predicting shock [52]

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Furthermore, we evaluated the protein levels of VE-cadherin and phosphorylation of FAK(y397) and Src(y418), which are closely associated with cell migration, invasion, and cytoskeletal rearrangement [62, 63]

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4 (T4), which is found in nearly all mammalian cells