glutathion s transferase Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation Glutathione S-transferase π: a potential
Description
In addition, mitochondrial protease Lon peptidase 1 (LONP1) inhibits Nrf2-mediated GPX4 gene expression, thereby promoting Erastin-induced ferroptosis in human PDAC cells (Wang H
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Meanwhile, the accumulation of ROS, release of mtDNA, and activation of inflammasome establish a potential self-reinforcing cycle of energy deficiency and inflammation, which may contribute to the delayed and persistent nature of PEM symptoms
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