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thesis, University of Saskatchewan, Saskatoon, SK

These methods reveal that astrocyte Ca 2+ elevations, triggered by mechanical or electrical stimuli, drive glutamate release to modulate neuronal activity via ionotropic (iGluR) or metabotropic (mGluR) receptors, as seen in hippocampal slices where astrocyte Ca 2+ waves inhibit or enhance presynaptic neurotransmission, highlighting context-dependent metabolic coupling in physiological and stress conditions (Chen et al., 2023)

For calcium imaging studies, male Naval Medical Research Institute (NMRI) mice (Taconic Biosciences, BomTac:NMRI) were used (aged 1828 days)

NAC FOR CONTRAST-INDUCED NEPHROPATHY The intravascular administration of contrast media for radiologic imaging techniques can result in acute renal dysfunction [176]