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Methods In this narrative review, data collection techniques included a comprehensive search of English peer-reviewed literature from January 1995 to January 2025 to ensure that an extensive range of studies addressing the microbiome and ME/CFS were included

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As part of shared decision-making, clinicians should counsel patients on all applicable options, with their risks and benefits

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The pharmacological opposition makes the combination less predictable

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The following data were collected: publication year, country and continent, study setting (e.g., hospital, private practice, academic clinic), sample size, age range, mean age, study design, population characteristics, intervention details, outcomes, and effect measures (e.g., serum B12 levels)

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