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After 1 h of co-incubation on ice at pH 6.5, most AsiG co-localized with the tumor cell membrane along with some red fluorescence dispersing in the cytoplasm, suggesting the aptamer-facilitated cell-targeting and cellular uptake of siG

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Invest Ophthalmol Vis Sci 59(9):19601960 Kaiser PK, Boyer DS, Campochiaro PA, Heier J, Kornfield J, Kuppermann BD et al (2017) Topline results from prospective, double-masked, placebo controlled phase 2b clinical study evaluating Luminate in patients with diabetic macular edema

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It was a leap of faith for the 46-year-old African American woman to participate in a clinical trial for breast cancer at Hartford Hospital

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