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Description
Fatty acids from adipose tissue travel to the liver and activate -oxidation creating acetyl-CoA which activates KB synthesis
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The blood lipids (e.g., free fatty acid and triglyceride) and cytokines (e.g., leptin) in mice with global AR knockout (ARKO) or tissue-specific knockout (e.g., liver and skeletal muscle) are significantly increased, and they are prone to suffer from obesity, insulin resistance (IR), and liver fibrosis ( As the metabolic center of energy substrates, mitochondria produce a large amount of adenosine triphosphate (ATP) to meet the energy needs of cells
Table 2 Ninety-one intersection gene targets obtained using the R software are listed below
Clinical Anatomy (New York, N.Y.) , 30 (1), 613
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