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Kidney Dysfunction: Higher levels of glutathione can damage or impair the kidney
Our identification of ketovaline (BCAA) and four acylcarnitines (isovaleryl-, hexanoyl-, tetradecanoyl-carnitine) as fasting markers, supports the notion that increased BCAAs and carnitines are required to maintain the metabolic activity of mitochondria through their conversion to acetyl-CoA and the transport of fatty acids into mitochondria, respectively
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In: Glutathione, p
doi: 10.1084/jem.20201129 289 VinciguerraM.RomitiS.FattouchK.De BellisA.GrecoE
Not only can the expression of these TJ proteins be influenced but also their localization within the cell can be dysregulated
