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These findings suggest that NNMT inhibition may influence tumor cell line phenotypes in vitro through both metabolic and epigenetic mechanisms, making 5-amino-1MQ a valuable tool for investigating the metabolic characteristics of different tumor cell lines

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It is commonly investigated in preclinical research models relating to metabolic signalling pathways, cellular energy regulation, and enzymatic activity associated with nicotinamide N-methyltransferase (NNMT) interaction studies

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