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Description
First, by inhibiting system Xc , Erastin causes a drastic reduction in GSH levels, leading to the inactivation of GPX4 and the accumulation of lipid peroxides, thus inducing and amplifying ferroptosis
When stapes fixation occurs, the stapes is unable to vibrate and transmit sound
Beyond direct neurological effects, KD may enhance levodopa efficacy by improving its bioavailability and appears to play a crucial role in modulating gut microbiota dysbiosis, a frequently observed and potentially contributing factor in PD
Janneke Balk, John Innes Centre, Norwich, UK for sharing the nramp3nramp4 double mutant with us
doi: 10.2217/pgs-2017-0055
