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Therefore, it follows that mitochondrial cysteine S -conjugate -lyases may be particularly important in bioactivating toxic cysteine S -conjugates

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Given that glutathione concentration can clearly increase in response to decreases in GSH:GSSG, it is unclear why the GSH:GSSG ratio does not seem to increase to compensate for decreases in glutathione concentration

10.1016/j.biopha.2020.110075 Summary Keywords sinapic acid, ethanol, oxidat ive stress, inflammation, Nrf2/HO-1 signaling pathway, gastric mucosal lesions Citation Raish M, Shahid M, Bin Jardan YA, Ansari MA, Alkharfy KM, Ahad A, Abdelrahman IA, Ahmad A and Al-Jenoobi FI (2021) Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-B Signaling and Antiapoptotic Role