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Palmitate oxidation rates were detected at 28 C using two media as already described 59 , the first media allowing both mitochondrial and peroxisomal -oxidation to occur, and the second one allowing peroxisomal -oxidation only

Several clinical trials have shown that PEA can reduce pain from a broad array of causes, including diabetic neuropathy, chemotherapy-induced peripheral neuropathy, sciatic nerve compression, carpal tunnel syndrome, osteoarthritis, low back pain, failed back surgery, stroke-related nerve pain, multiple sclerosis, dental pain, chronic pelvic pain, post-herpetic neuralgia, and vaginal pain (Hesselink 2012)

This means your entire body needs it to function properly and a deficiency can lead to costly physiological and psychological consequences, including addiction

All relevant data are within the paper and its Supporting Information files