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In particular, xCT and mGluR2 downregulation at the hippocampal level correlates with depressive and low resilience phenotypes to stress [165], and the reduced expression of mGluR2 may provide insights into the virus-induced vulnerability to stress-related conditions [20, 168]

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

Apoptosis-inducing factor, mitochondrion-associated 2, regulates Klf1 in a mouse erythroleukemia cell line

doi: 10.12659/MSM.881792

Cell Biol Toxicol2026 May 29

In the pathogenesis of MASLD, the oxidation of accumulated fatty acids in hepatocytes leads to increased ROS production and subsequent formation of MDA [132]
