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Activation of the NRF2/SLC7A11/GPX4 signaling pathway leads to elevated GSH levels, reduced MDA and ROS accumulation, suppression of neuronal ferroptosis, lipid peroxidation, and amino acid antioxidant dysfunction, ultimately mitigating neuronal injury

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doi: 10.1016/j.brainres.2019.146509 159 QinCFanWHLiuQShangKMuruganMWuLJet al

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The molecular mechanisms regulating the KEAP1-NRF2 pathway