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Rothstein prefers people get their vitamins from diet, not from supplements, as vitamins from foods are best absorbed by the body

(iii) toxicokinetic studies for the determination of the absorption, distribution, metabolism, and excretion of contaminants (Asam et al

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Bernink, J

No long-term safety data beyond 6 months

These involve substantial volume loss, dermal thinning, and sometimes underlying fat pad changes that topical treatments alone cannot fully address