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What is nonodontogenic tooth pain

Statements Author contributions JS, RS, EH, and HG conceived and designed the study, revised the manuscript, and read and approved the submitted version

2021;184:416885.e21

doi: 10.1172/JCI113450 110 NorrelundHFrystykJJorgensenJOMollerNChristiansenJSOrskovHet al

It is important to consult a healthcare provider if fatigue is persistent, worsening, or interfering with daily life

Oxidative stress or other stress stimuli induce the dissociation of the Nrf2-Keap1 complex, resulting in Nrf2 nuclear translocation and subsequent binding to the antioxidant response element (ARE) in the regulatory region of the target genes