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The Glutathione System: A New Drug Target in Neuroimmune Disorders. Molecular Neurobiology, vol

The supply pathway involves the export of GSH from astrocytes via the multidrugresistance protein 1 (Mrp1), extracellular processing of GSH by astrocytic glutamyl transpeptidase (GT) to the dipeptide cysteinylglycine (CysGly) and hydrolysis of this dipeptide by neuronal aminopeptidase N (ApN) to cysteine (Cys) and glycine (Gly)

Pigment Cell Melanoma Res 37(4):438452

CHAC1 functions as a -glutamylcyclotransferase catalysing glutathione degradation 39

NF-B signaling pathway The NF-B signaling pathway plays a pivotal role in biological processes such as the immune response, cell proliferation, and apoptosis