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Moreover, most of the so far documented direct or indirect inhibitors of GPX4 may also affect other cellular processes not directly linked to ferroptosis induction leading to potentially detrimental side effects in patients

Int J Food Microbiol 191:3235

Our main interest is to understand the synthesis and export of GSH in liver cells and how intracellular metabolite balance is affected by oxidative stress

In lean adult mice, the expression of NDI1 in adipocytes had no impact on body weight, glucose homeostasis, the expression of mature adipocyte and thermogenic markers, or histological features of adipose depots (Extended Data Fig

Factors like high stress, poor nutrition, and environmental toxins can deplete our natural stores faster than the body can replenish them