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Both genes encode for transcription factors that regulate megakaryopoiesis, and defects result in enlarged platelets with fewer (though not absent) -granules, as studies in additional GATA1 and GFI1B patients illustrated.1813 Based on a recent detailed comparison of clinical and laboratory data for NBEAL2, GATA1 and GFI1B patients,3 it was suggested not to use the term GPS for other macrothrombocytopenia disorders that comprise abnormal -granule numbers, except for patients with NBEAL2 defects

Therefore, each BRD has a preference for different histones

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus

Psychopharmacology 228 , 419426 (2013)

In inflammatory diseases, T cells that are deficient in GLS are not fully activated and quickly become depleted (36)