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It was reported that combination of nanaomycin A, a selective DNMT3B inhibitor, with FGF4 and BMP4 promoted the differentiation from DE to HPCs (Nakamae et al., 2018)
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Mueller NT, Jacobs DR Jr, MacLehose RF, Demerath EW, Kelly SP, Dreyfus JG, Pereira MA

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A., Dubrulle J., Moens C
