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Niacinamide: An antioxidant that increases energy levels and is an NAD precursor

Histamine is the key inflammatory mediator, but other substances are also released by mast cells, including PAF, eicosanoids, prostaglandins, leukotrienes, substance P, and ROS

Chronic stress sustained cortisol elevation depletes glutathione along with several other antioxidant reserves

Oral Radiol
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doi: 10.1016/j.molcel.2017.03.004