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Serum was separated by centrifugation at 4,000 g for 10 min (Model 5402

in a bile duct ligation (BDL) rat model of chronic cholestasis confirmed that the concentration of GSH and ubiquinone decreases during cholestasis, whereas an increase in lipid peroxidation is observed [183]

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Biological & Pharmaceutical Bulletin

Evaluation of free radical-scavenging and antioxidant properties of black berry against fluoride toxicity in rats Oxidative damage to cellular components such as lipids and cell membranes by free radicals and other reactive oxygen species is believed to be associated with the development of degenerative diseases