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One study published in the American Journal of Clinical Nutrition in 2002 found that betaine supplementation led to significant reductions in homocysteine levels in participants with high homocysteine levels

doi: 10.1007/s11481-012-9431-7

& Phutdhawong, W

Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency

Cut out afternoon caffeine, and avoid large, heavy meals and alcohol later in the evening, both of which can negatively affect sleep
