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Visceral adipose tissue targeting: visceral fat the fat stored around internal organs that drives metabolic disease risk is metabolically active and more responsive to insulin-sensitizing interventions than subcutaneous fat

In the presence of OsDHAR, there was a significant increase in CAT enzymatic activity compared to in the presence of LYS or CRY, which were used as negative and positive controls, respectively (Fig

Liberated during heme catabolism by HO-1, iron is sequestered within ferritin nanocages in its non-reactive ferric state (Fe 3+ ), distinct from the redox-active ferrous form (Fe 2+ ) (156)

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BioMedicine 6, 20

[24] Such abnormalities could occur in any number of the nine implicated pathways (clotting cascade, antioxidant pathways, apoptosis, inflammatory cytokines, angiogenesis and vascular remodelling, growth factors, surfactant and matrix regulatory factors), [24] and that through further investigation into all nine, novel therapies and approaches could be proposed on a unique or case-by-case basis should attempts at treating or circumventing complications in any one pathway prove unsuccessful