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On the other hand, glutarate hydroxylase CsiD is subject to weak product inhibition (Knorr et al., Moreover, a weak substrate inhibition on l-2HG production by glutarate could also be identified (Figure 5B)
(2022) 63:E93101
After obtaining 4-hydroxythalidomide, it is possible to form ether bond-containing derivatives through its reaction with a linker whose terminus is iodine, bromine or tosylate group (compound 58 ) 79,113,114,115
PMN-MDSCs are more susceptible to ferroptosis than neutrophils in the spleen or bone marrow because of the intracellular redox imbalance caused by ROS/reactive nitrogen species (RNS) -generating machinery (Kim 2022)
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Next, we investigated whether PDP1 is regulated by ROS, given that both protein phosphatases (Sommer et al., 2002
