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Description
Lipoylated protein aggregation is associated with the destruction of iron-sulfur cluster proteins, commonly initiated by ROS [54]

In addition, the above findings indicate that DMSA monoesters are a superior treatment option to DMSA on its own in terms of eliciting recovery from altered biochemical variables and causing depletion of body lead and cadmium burden

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Current protocols are based on preclinical extrapolation, anecdotal clinical experience, or single-dose pharmacokinetic studies rather than on systematic dose-finding trials ( Third, the effects of combination therapy are unexplored
