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doi: 10.1016/j.mrfmmm.2004.06.056

Thus, interactions between nerve biochemistry and perfusion defects from STZ-induced diabetes, corrected by ALA, have differential impacts on nerve fiber populations

[3] It should be noted that, whereas activation of the first thiamine pyrophosphate results from its binding to the active site, activation of the second coenzyme, and thus of the second active site, is coupled to the decarboxylation of pyruvate in the first active site

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Mol Cell Biol (2002) 22(14):510013

This, in turn, can facilitate timely and appropriate interventions, potentially reducing the incidence of adverse outcomes, such as perforation and abscess formation