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Description
Metformin Metformin is a widely used anti-diabetes drug that activates the adenosine monophosphate activated protein kinase (AMPK) pathway

538 Aged astrocytes indeed express fewer glutamate transporters, resulting in age-dependent decreases in glutamate clearance

PMID: 6895513

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doi: 10.3389/fneur.2020.590573

To date, various therapeutic approaches have been recommended, but with moderate success
