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CNS Neurol Disord Drug Targets 10:149162 Hernndez-Aguilera A, Rull A, Rodrguez-Gallego E, Riera-Borrull M, Luciano-Mateo F et al (2013) Mitochondrial dysfunction: a basic mechanism in inflammation-related non-communicable diseases and therapeutic opportunities

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The structures of some isocereulides differed from that of cereulide by substitution of L- O -Val by L- O -Leu (isocereulide A), L-Val by L-Ala (isocereulide D), D-Ala by D-Ser (isocereulide C) and D- O -Leu by D- O -Val (isocereulide B), thus indicating a relaxed substrate specificity of the A domains and an inefficient proof reading by CesT 18