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However, the FDA has interpreted this study and put a warning on febuxostat that it should be used second line, after allopurinol
[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK

10.4049/jimmunol.1004030 J

Differential effect of catecholamines and MPP(+) on membrane permeability in brain mitochondria and cell viability in PC12 cells
334 These morphological aberrations are paralleled with loss of function

K.van DoormaalP
