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Safety Toxicity No toxic or adverse effects have been associated with large intakes of vitamin B 12 from food or supplements in healthy people

In the U.S., injectable B12 (cyanocobalamin and hydroxocobalamin) is only available with a prescription, as regulated by the FDA

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Recommended B12 Supplementation Following Gastric Sleeve Surgery Lifelong B12 supplementation is recommended after sleeve gastrectomy

However, it is imperative to understand that fragment 176-191 (AOD-9604) does not have any effect on the level of insulin or insulin resistance

Journal of Paediatrics and Child Health 2014;50(9):7215