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For shRNA ICC experiments, hippocampal astrocytes were transfected with AAV-pSicoR-Sc-shRNA or AAV-pSicoR-Hb-shRNA vectors via the NeoNTM transfection system and incubated for 710 days to allow transgene expression

A phase 1 study of VX-522 in participants with cystic fibrosis (CF) [EB/OL]

The mechanism of action is multifactorial, directly or indirectly upregulating cell growth, proliferation, survival, angiogenesis, and anti-inflammation pathways

doi: 10.1016/j.pestbp.2021.104860