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Specifically, ligation of the chemockine receptor CXCR4 on Schwann cells by gp120 resulted in the release of RANTES which induced the DRG neruons to produce TNF- and subsequent TNFR1-mediated neurotoxicity in an autocrine fashion 64

doi: 10.1186/s12937-024-00934-4, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 65.Akisu M, Ozmen D, Baka M, Habif S, Yalaz M, Arslanoglu S, et al

SCA1, 2, 3, and 6 are the most common SCAs (81)

doi: 10.1016/j.jnutbio.2009.07.008 109 SouzaLLCordeiroAOliveiraLSde PaulaGSFaustinoLCOrtiga-CarvalhoTMet al

Research-Ready Output for Biomarker & Mechanism Studies Data feed directly into metabolic pathway interpretation: fatty acid oxidation, branched-chain amino acid catabolism, mitochondrial dysfunction

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