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Vitamin D3, which is readily manufactured by the body when the skin is exposed to natural sunlight

For peptides, threshold varies by endpoint

10.1186/s13024-021-00463-2 58 OttoL

These disparities substantially limit data integration and model generalizability across research centers

It has been widely used in anti-aging and cosmetic products for decades without any adverse effects, and can be easily incorporated into creams, liposomes, foams, or subcutaneous injections

3.6 Integrated transcriptomicproteomic analysis 3.6.1 Overview of differential expression at transcriptomic and proteomic levels Among 17,251 genes analyzed, 116 DEGs (0.67%) were identified, comprising 41 up-regulated and 75 down-regulated genes