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Targeting DPP4 Although targeting compounds that can inhibit the enzymatic action of DPP4 would seem like ideal candidates for treating the hyperglycemia of uncontrolled diabetes, there are several unknowns associated with DPP4 inhibition

It decreased intestinal microbiota-dependent production of TMA/TMAO from l-carnitine in Wistar rats [56]

Lowy, E

Increased productivity was obtained using a genetically modified strain overproducing the multifunctional protein CaiD, which is part of both carnitine dehydratase (CDH) and carnitine racemase (CRac) activities [61]

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doi: 10.1016/j.molcel.2014.03.048 109 IvankovicDChauKYSchapiraAHGeggME