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Although it is known that the promoter regions of the genes encoding GLCL and GSTs possess binding sites for such transcriptional regulators as NF- B, AP-1, AP-2, SP-1, and others [192194], most attention has been concentrated on the Nrf2/Keap1 system [160, 195]

Conflict of interest The authors state no conflict of interest

doi: 10.1111/j.1432-1033.1969.tb00721.x

Key enzymes and transporters of lactate metabolism are altered in HCC

References 1 AhsanM

healthcare spending reached USD 4.9 trillion in 2023, representing 17.6% of GDP , highlighting the region's strong healthcare investment environment that supports the adoption of wellness and infusion-based therapies