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Moreover, metformin improves mitochondrial function and contributes to helping restore hormonal balance and insulin sensitivity in PCOS patients (Rabah et al., 2023)

Perturbation of these pathways is critical to many neurological disorders (NDs) such as Alzheimers disease (AD), Parkinsons disease (PD), Multiple sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), and Cerebral ischemia, indicating their involvement in the pathogenesis and advancement of these conditions (7)

Biol Psychiatry 62:13241333

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, Fraix V., Cavallieri F., et al

This library-independent dDIA strategy also worked well with twofold increase in precursors matched and 75% increase in phosphopeptides (Fig