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Pyridostigmine pretreatment does not confer an advantage against sarin Contraindications: Mechanical intestinal or urinary obstruction Particular caution should be used in its administration to patients with bronchial asthma Side Effects:

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This indicates that the urinary bladder is regulated by neural mechanisms ( Epithelial dysfunction The urinary bladders lining includes a bladder surface mucin that is impermeable and made up of sulfonated glycosaminoglycans (GAGs) and glycoproteins