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Neuroprotection in traumatic brain injury

[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Campbell J.D., McDonough J.E., Zeskind J.E., Hackett T.L., Pechkovsky D.V., Brandsma C.A., Suzuki M., Gosselink J.V., Liu G., Alekseyev Y.O., et al

Biomedical Mass Spectrometry

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Clinical trials have demonstrated that supplementation with coenzyme Q10 reduces the severity, frequency, and duration of migraine attacks, with effects typically observed within 4 weeks (9294)
Mitochondrial-mediated ROS cause oxidative damage to cellular structures, particularly mitochondrial DNA, somatic mutations, genome instability, inactivation of tumor suppressor genes, alterations in metabolic and signaling pathways with simultaneous activation of compensatory antioxidant mechanisms, all of which contribute to cell transformation and thus promote various types of cancer [42]
